Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLK | Q9H2G2 | 6/20 | 0.42 |
| ▸ | STK10 | O94804 | 5/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7444756 | 0.88 | FYN (0.39) | SLKSTK10CLK4CLK2GSK3A | |
| SCHEMBL627191 | 0.76 | RAB9A (0.35) | SLKSTK10CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL7303598 | 0.69 | CA12 (0.35) | CYP1A2CYP3A4CYP2C19ALDH1A1CYP2D6 | |
| SCHEMBL9469524 | 0.69 | HTR7 (0.55) | SLKSTK10CLK4CLK2GSK3A | |
| SCHEMBL7209808 | 0.69 | CA2 (0.46) | SLKSTK10ALDH1A1MAPK1USP2 | |
| SCHEMBL7296783 | 0.69 | DDB1 (0.37) | ALDH1A1PDE4D | |
| SCHEMBL7201836 | 0.69 | CA12 (0.34) | SLKSTK10CYP3A4ALDH1A1MEN1 | |
| SCHEMBL13430583 | 0.68 | — | — | |
| SCHEMBL7330474 | 0.67 | MAPT (0.33) | CYP1A2CYP2C19ALDH1A1CYP2D6USP2 | |
| SCHEMBL7197852 | 0.67 | SIRT2 (0.49) | ALDH1A1USP2MEN1KMT2APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799209-B1 | SULFONAMIDES | HOFFMANN LA ROCHE (CH) | 2003-08-06 | — | — | EP | disclosed |
| US-6004965-A | Sulfonamides | HOFFMANN-LA ROCHE INC. (US) | 1999-12-21 | — | — | US | disclosed |