Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6959081 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KDM4EL3MBTL1ATMSMN1; SMN2 | |
| Oxalic Acid SCHEMBL6959493 | 0.91 | KDM4E (0.51) | ALDH1A1KDM4EL3MBTL1ATMSMN1; SMN2 | |
| Oxalic Acid SCHEMBL6970867 | 0.90 | KDM4E (0.47) | ALDH1A1KDM4ESMN1; SMN2CYP2D6MEN1 | |
| SCHEMBL7813214 | 0.90 | ALDH1A1 (0.52) | ALDH1A1KDM4EL3MBTL1ATMSMN1; SMN2 | |
| SCHEMBL6963106 | 0.87 | SLC6A1 (0.44) | ALDH1A1SMN1; SMN2CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL6957114 | 0.87 | SLC6A1 (0.44) | ALDH1A1SMN1; SMN2CYP2C19CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL6958333 | 0.86 | LMNA (0.45) | ALDH1A1SMN1; SMN2CYP2C19CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL6957875 | 0.86 | LMNA (0.45) | ALDH1A1SMN1; SMN2CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL8720453 | 0.86 | ALDH1A1 (0.56) | ALDH1A1KDM4EL3MBTL1ATMSMN1; SMN2 | |
| Oxalic Acid SCHEMBL8720463 | 0.83 | TBXA2R (0.53) | ALDH1A1KDM4EL3MBTL1ATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934313-B1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK AS (DK) | 2003-05-14 | — | — | EP | disclosed |
| US-6004983-A | ANALGESICS; ANTIINFLAMMATORY, ANTIARTHRITIC AND ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DE) | 1999-12-21 | — | — | US | disclosed |
| EP-0934313-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998015549-A1 | N-SUBSTITUTED AZAHETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-04-16 | — | — | WO | disclosed |