Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6969816 | 0.90 | RAB9A (0.54) | TBXA2RHRH1ALDH1A1KDM4ERAB9A | |
| SCHEMBL8717428 | 0.87 | TBXA2R (0.60) | TBXA2RHRH1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL8720453 | 0.87 | ALDH1A1 (0.56) | ALDH1A1KDM4EL3MBTL1ATMCYP1A2 | |
| Hydrochloric Acid SCHEMBL7609379 | 0.86 | TBXA2R (0.59) | TBXA2RHRH1ALDH1A1 | |
| Oxalic Acid SCHEMBL6964376 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4EL3MBTL1ATMCYP1A2 | |
| Oxalic Acid SCHEMBL6959081 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4EL3MBTL1ATMCYP1A2 | |
| SCHEMBL7472327 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4EL3MBTL1ATMSMN1; SMN2 | |
| SCHEMBL7468646 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KDM4EL3MBTL1ATMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7473576 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4EL3MBTL1ATMSMN1; SMN2 | |
| Oxalic Acid SCHEMBL6959493 | 0.79 | KDM4E (0.51) | ALDH1A1KDM4EL3MBTL1ATMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869777-A1 | NOVEL METHOD | NOVO NORDISK A/S (DK) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997022338-A1 | NOVEL METHOD | NOVO NORDISK A/S (DK) | 1997-06-26 | — | — | WO | disclosed |