Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225262 | 0.88 | KMT2A (0.47) | FADS1MAPTROCK2TSHRALOX15 | |
| Water SCHEMBL2910884 | 0.86 | KMT2A (0.45) | FADS1MAPTROCK2TSHRALOX15 | |
| SCHEMBL5969405 | 0.74 | KMT2A (0.59) | MAPTTSHRKMT2AMEN1RECQL | |
| SCHEMBL8495437 | 0.73 | ATM (0.51) | MAPTKMT2AMEN1CYP19A1CTSG | |
| SCHEMBL8495439 | 0.73 | ATM (0.51) | MAPTKMT2AMEN1CYP19A1CTSG | |
| SCHEMBL29187460 | 0.72 | ALOX15 (0.45) | FADS1MAPTTSHRALOX15KMT2A | |
| SCHEMBL29187457 | 0.72 | ALOX15 (0.45) | FADS1MAPTTSHRALOX15KMT2A | |
| SCHEMBL4721528 | 0.70 | ROCK2 (0.62) | ROCK2TSHRKMT2AMEN1 | |
| SCHEMBL8494181 | 0.70 | POLB (0.50) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL2800406 | 0.70 | POLB (0.50) | KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362855-A1 | BETA-LACTAM COMPOUNDS, PROCESS FOR REPODUCING THE SAME AND SERUM CHOLESTEROL-LOWERING AGENTS CONTAINING THE SAME | Kotobuki Pharmaceutical Co., Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |