Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CCNC | P24863 | 2/20 | 0.43 |
| ▸ | CDK8 | P49336 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.40 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22784143 | 0.79 | CCNC (0.51) | KDM4EHPGDTSHRHSD17B10CCNC | |
| SCHEMBL6995037 | 0.75 | L3MBTL1 (0.44) | KDM4ETSHRL3MBTL1ALDH1A1TAAR1 | |
| SCHEMBL6971345 | 0.72 | KMT2A (0.55) | CCNCCDK8ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL3288225 | 0.70 | NPC1 (0.63) | KDM4EHPGDTSHRHSD17B10CCNC | |
| SCHEMBL27604839 | 0.70 | KMT2A (0.52) | CCNCCDK8SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5544020 | 0.70 | L3MBTL1 (0.70) | TSHRL3MBTL1ALDH1A1TAAR1SMN1; SMN2 | |
| SCHEMBL27463401 | 0.69 | L3MBTL1 (0.63) | KDM4ETSHRL3MBTL1ALDH1A1TAAR1 | |
| SCHEMBL28093432 | 0.69 | KDM4E (0.39) | KDM4EHPGDTSHRHSD17B10L3MBTL1 | |
| SCHEMBL6216630 | 0.68 | L3MBTL1 (0.43) | KDM4EHPGDTSHRHSD17B10CCNC | |
| SCHEMBL6971569 | 0.68 | ROCK2 (0.38) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |