Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.51 |
| ▸ | DRD4 | P21917 | 14/20 | 0.51 |
| ▸ | DRD3 | P35462 | 14/20 | 0.51 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965928 | 0.92 | DRD2 (0.59) | DRD2DRD4DRD3GRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL6972143 | 0.91 | DRD2 (0.58) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL6955492 | 0.90 | DRD2 (0.54) | DRD2DRD4DRD3HRH1GRIN1 | |
| SCHEMBL6966798 | 0.87 | DRD2 (0.54) | DRD2DRD4DRD3HRH1GRIN1 | |
| Hydrochloric Acid SCHEMBL6973026 | 0.86 | DRD2 (0.53) | DRD2DRD4DRD3HRH1GRIN1 | |
| Oxalic Acid SCHEMBL6959134 | 0.84 | DRD2 (0.53) | DRD2DRD4DRD3HRH1 | |
| SCHEMBL6964674 | 0.79 | DRD2 (0.48) | DRD2DRD4DRD3CHRM1 | |
| SCHEMBL6965133 | 0.78 | DRD2 (0.62) | DRD2DRD4DRD3GRIN1GRIN2B | |
| Hydrochloric Acid SCHEMBL6959218 | 0.77 | DRD2 (0.61) | DRD2DRD4DRD3GRIN1GRIN2B | |
| SCHEMBL7087330 | 0.77 | DRD2 (0.56) | DRD2DRD4DRD3GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934312-B1 | 1,4-DISUBSTITUTED PIPERAZINES | NOVO NORDISK AS (DK) | 2003-03-19 | — | — | EP | claimed |