Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964297 | 0.83 | HDAC3 (0.60) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL16438824 | 0.80 | HDAC3 (0.68) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL400890 | 0.79 | RAB9A (0.77) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL3247730 | 0.78 | ALOX15 (0.54) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL12324391 | 0.77 | RAB9A (0.82) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL6967578 | 0.74 | RAB9A (0.63) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL11298577 | 0.74 | RAB9A (0.75) | CA1CA9POLBKDM4ERAB9A | |
| SCHEMBL28875360 | 0.73 | SMN1; SMN2 (0.71) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL3724445 | 0.73 | RAB9A (0.68) | HDAC3CA12CA1IDO1ALOX15 | |
| SCHEMBL28308054 | 0.73 | RAB9A (0.61) | HDAC3CA12CA1IDO1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867787-A | Insulin producing cells | 武田药品工业株式会社 | 2021-05-28 | — | — | CN | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |