Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | DRD1 | P21728 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 11/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440055 | 0.89 | PSMB1 (0.68) | DRD2DRD1DRD3PSMB1PSMB5 | |
| SCHEMBL7346853 | 0.84 | PSMB1 (0.54) | DRD2DRD1DRD3PSMB1PSMB5 | |
| SCHEMBL6966422 | 0.79 | L3MBTL1 (0.53) | DRD2DRD1DRD3PSMB1PSMB5 | |
| SCHEMBL6968065 | 0.78 | TDP1 (0.55) | DRD2DRD1DRD3MEN1KMT2A | |
| SCHEMBL6961322 | 0.77 | HRH1 (0.51) | DRD2DRD1DRD3PSMB1PSMB5 | |
| SCHEMBL23038800 | 0.72 | TSHR (0.61) | DRD2DRD1DRD3LTA4HSMN1; SMN2 | |
| SCHEMBL6597214 | 0.70 | PSMB1 (0.97) | PSMB1PSMB5PSMB2LTA4HKDM4E | |
| SCHEMBL7451698 | 0.70 | POLB (0.58) | DRD2DRD1DRD3LTA4HMEN1 | |
| SCHEMBL7352552 | 0.69 | LTA4H (0.65) | DRD2DRD1DRD3PSMB1PSMB5 | |
| SCHEMBL28380360 | 0.69 | LTA4H (1.00) | DRD2DRD1DRD3PSMB1PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |