Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 4/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | HRH1 | P35367 | 3/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | DRD5 | P21918 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23038800 | 0.82 | TSHR (0.61) | TDP1TSHRCYP2D6CYP2C19CYP1A2 | |
| SCHEMBL7451698 | 0.79 | POLB (0.58) | TDP1TSHRCYP2D6CYP2C19CYP1A2 | |
| SCHEMBL6961322 | 0.79 | HRH1 (0.51) | TDP1TSHRDRD1DRD3DRD2 | |
| SCHEMBL6967272 | 0.78 | DRD2 (0.56) | TDP1TSHRCYP2D6CYP2C19HSD17B10 | |
| SCHEMBL29573150 | 0.78 | TDP1 (0.66) | TDP1TSHRCYP2D6CYP2C19CYP1A2 | |
| SCHEMBL14397182 | 0.76 | TSHR (0.67) | TDP1TSHRCYP2D6CYP2C19CYP1A2 | |
| SCHEMBL7440055 | 0.74 | PSMB1 (0.68) | DRD1DRD3DRD2KDM4EALDH1A1 | |
| SCHEMBL9086872 | 0.74 | MAPT (0.38) | CYP2C19CYP1A2POLBKDM4ESMN1; SMN2 | |
| SCHEMBL7447035 | 0.73 | PSMB1 (0.64) | DRD1DRD3DRD2HRH1DRD4 | |
| SCHEMBL956747 | 0.73 | LTA4H (0.51) | TDP1TSHRCYP2D6CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-1244655-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001036414-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2001-05-25 | — | — | WO | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |