Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 7/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957113 | 0.82 | LTA4H (0.45) | L3MBTL1LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL7440055 | 0.82 | PSMB1 (0.68) | LTA4HPSMB1PSMB5PSMB2GCGR | |
| SCHEMBL7139717 | 0.80 | L3MBTL1 (0.54) | L3MBTL1LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL6967272 | 0.79 | DRD2 (0.56) | LTA4HPSMB1PSMB5PSMB2MEN1 | |
| SCHEMBL7346853 | 0.79 | PSMB1 (0.54) | LTA4HPSMB1PSMB5PSMB2MEN1 | |
| SCHEMBL7412759 | 0.76 | ESR1 (0.72) | MEN1KMT2ADRD2DRD1DRD3 | |
| SCHEMBL6955429 | 0.69 | L3MBTL1 (0.51) | L3MBTL1LTA4HPSMB1PSMB5PSMB2 | |
| SCHEMBL6977670 | 0.69 | PKM (0.53) | L3MBTL1MEN1KMT2AKDM4EPKM | |
| SCHEMBL23488108 | 0.68 | SMN1; SMN2 (0.57) | L3MBTL1MEN1KMT2APKM | |
| SCHEMBL6597214 | 0.67 | PSMB1 (0.97) | LTA4HPSMB1PSMB5PSMB2GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |