Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.53 |
| ▸ | PPARA | Q07869 | 15/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746469 | 0.85 | PPARG (0.73) | PPARGPPARAPPARD | |
| SCHEMBL6970285 | 0.84 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL6978745 | 0.83 | PPARG (0.54) | PPARG | |
| SCHEMBL6157782 | 0.82 | FFAR1 (0.65) | PPARGPPARA | |
| SCHEMBL7133082 | 0.77 | PPARG (0.45) | PPARGPPARAPPARD | |
| SCHEMBL6968221 | 0.77 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL6967717 | 0.76 | TSHR (0.69) | — | |
| SCHEMBL7165258 | 0.75 | PPARG (0.69) | PPARGPPARAPPARD | |
| SCHEMBL9316609 | 0.75 | LMNA (0.52) | PPARGPPARARAB9APPARD | |
| SCHEMBL7165255 | 0.75 | PPARG (0.69) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801063-B1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDYS LAB LTD DR (IN) | 2003-01-15 | — | — | EP | disclosed |
| EP-0801063-A1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-10-15 | — | — | EP | disclosed |