SCHEMBL6967486

SCHEMBL6967486

Cc1nnsc1C(=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.61
GAA P10253 4/20 0.54
ALDH1A1 P00352 5/20 0.52
POLB P06746 4/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
MAPT P10636 5/20 0.51
TDP1 Q9NUW8 2/20 0.51
USP2 O75604 1/20 0.51
ATM Q13315 1/20 0.51
CHRM4 P08173 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
AGTR1 P30556 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27417482 0.80 KDM4E (0.41) LMNAGAAALDH1A1POLBMEN1
SCHEMBL7043652 0.76 LMNA (1.00) LMNAGAAALDH1A1POLBMEN1
SCHEMBL24467887 0.75 LMNA (0.50) LMNAGAAALDH1A1POLBMEN1
SCHEMBL27972473 0.73 RAB9A (0.63) GAAALDH1A1POLBMEN1KMT2A
SCHEMBL8633207 0.73 KDM4E (0.61) LMNAALDH1A1POLBMEN1KMT2A
SCHEMBL11538782 0.73 LMNA (0.62) LMNAGAAALDH1A1POLBMEN1
SCHEMBL18924216 0.73 TSHR (0.56) LMNAGAAALDH1A1POLBMEN1
SCHEMBL11543097 0.72 ATM (0.70) LMNAALDH1A1MEN1KMT2AATM
SCHEMBL11571990 0.72 MAPT (0.56) LMNAGAAALDH1A1POLBMEN1
SCHEMBL11571174 0.71 MAPT (0.52) LMNAGAAALDH1A1POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0930305-B1 1,2,3-THIADIAZOLE DERIVATIVES AND SALTS THEREOF, DISEASE CONTROLLING AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE, AND METHOD FOR THE USE THEREOF NIHON NOHYAKU CO LTD (JP) 2003-05-14 EP disclosed
US-6337341-B1 AGROHORTICULTURAL DISEASE CONTROLLER CONTAINING SAID COMPOUND AS AN ACTIVE INGREDIENT, AND METHOD FOR USING THE DISEASE CONTROLLER. NIHON NOHYAKU CO., LTD. (JP) 2002-01-08 US disclosed
US-6194444-B1 FUNGICIDES, BACTERICIDES, VIRICIDES NIHON NOHYAKU CO., LTD (JP) 2001-02-27 US disclosed
EP-0930305-A1 1,2,3-THIADIAZOLE DERIVATIVES AND SALTS THEREOF, DISEASE CONTROLLING AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE, AND METHOD FOR THE USE THEREOF Nihon Nohyaku Co., Ltd. (JP) 1999-07-21 EP disclosed