Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 2/20 | 0.39 |
| ▸ | MAX | P61244 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 9/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968608 | 0.92 | MYC (0.36) | MYCMAXKDM4EMAPTMMP13 | |
| SCHEMBL6970220 | 0.86 | MYC (0.38) | MYCMAXKDM4EMMP13MMP1 | |
| SCHEMBL6977003 | 0.86 | LMNA (0.40) | MYCMAXKDM4EMMP13GPR119 | |
| SCHEMBL6966272 | 0.85 | MYC (0.42) | MYCMAXKDM4EMMP13GPR119 | |
| SCHEMBL7951214 | 0.85 | TGFBR1 (0.44) | KDM4EMMP13MMP1GPR119PKM | |
| SCHEMBL6964258 | 0.85 | MMP13 (0.50) | MYCMAXKDM4EMMP13MMP1 | |
| SCHEMBL6962383 | 0.84 | MMP13 (0.41) | MYCMAXKDM4EMAPTMMP13 | |
| SCHEMBL6968609 | 0.84 | GPR119 (0.39) | MYCMAXKDM4EMMP13GPR119 | |
| SCHEMBL6964185 | 0.84 | GPR119 (0.48) | MMP13MMP1GPR119 | |
| SCHEMBL6963440 | 0.84 | CYP3A4 (0.41) | MYCMAXKDM4EMMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |