Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27962934 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HTTPIK3CDPIK3CAPIK3CB | |
| SCHEMBL6199512 | 0.77 | L3MBTL1 (0.33) | — | |
| SCHEMBL6963366 | 0.75 | ALDH1A1 (0.48) | ALDH1A1HTTPOLB | |
| SCHEMBL1448807 | 0.74 | L3MBTL1 (0.44) | ALDH1A1 | |
| SCHEMBL514821 | 0.74 | ALDH1A1 (0.63) | ALDH1A1HTTPOLB | |
| SCHEMBL442816 | 0.74 | HSD11B1 (0.33) | — | |
| SCHEMBL1448415 | 0.72 | CCR2 (0.33) | — | |
| SCHEMBL2903043 | 0.72 | L3MBTL1 (0.38) | — | |
| SCHEMBL232460 | 0.70 | — | — | |
| SCHEMBL408050 | 0.69 | TSHR (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |