Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 5/20 | 0.42 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.41 |
| ▸ | KCNJ8 | Q15842 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1146161 | 0.80 | HSD11B1 (0.59) | ALDH1A1LMNAHPGDKDM4EHSD11B1 | |
| SCHEMBL5454671 | 0.77 | HTR6 (0.46) | ALDH1A1HSD11B1HTR6ABCC9ABCC8 | |
| SCHEMBL4783767 | 0.76 | HTR6 (0.61) | ALDH1A1LMNAHPGDKDM4EHTR6 | |
| SCHEMBL28252471 | 0.76 | HTR6 (0.45) | ALDH1A1LMNAKDM4EHSD11B1HTR6 | |
| SCHEMBL22028032 | 0.76 | POLB (0.50) | ALDH1A1HTR6ABCC9ABCC8KCNJ11 | |
| SCHEMBL6967553 | 0.75 | ALDH1A1 (0.37) | ALDH1A1POLBHTT | |
| SCHEMBL28330197 | 0.74 | HTR6 (0.46) | ALDH1A1KDM4EHSD11B1HTR6KMT2A | |
| SCHEMBL1691772 | 0.72 | HTR6 (0.45) | ALDH1A1LMNAHSD11B1HTR6KMT2A | |
| SCHEMBL10692275 | 0.72 | ALDH1A1 (0.57) | ALDH1A1LMNAHPGDKDM4EHSD11B1 | |
| SCHEMBL6971370 | 0.72 | KMT2A (0.68) | ALDH1A1HTR6ABCC9ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |