Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965972 | 0.88 | SMN1; SMN2 (0.42) | PPARGLMNAALDH1A1MEN1RAB9A | |
| SCHEMBL6970661 | 0.88 | ALDH1A1 (0.46) | PPARGLMNAALDH1A1NPSR1USP2 | |
| SCHEMBL6969382 | 0.86 | LMNA (0.55) | PPARGLMNAALDH1A1NPSR1USP2 | |
| SCHEMBL6969797 | 0.86 | LMNA (0.44) | PPARGLMNAALDH1A1NPSR1DPP4 | |
| SCHEMBL6962852 | 0.85 | CA1 (0.43) | PPARGLMNAALDH1A1NPSR1USP2 | |
| SCHEMBL6960127 | 0.85 | NPSR1 (0.49) | PPARGLMNAALDH1A1NPSR1NOTUM | |
| SCHEMBL6969459 | 0.84 | ALDH1A1 (0.46) | PPARGLMNAALDH1A1NPSR1USP2 | |
| SCHEMBL6957268 | 0.80 | AVPR2 (0.56) | — | |
| SCHEMBL6968111 | 0.78 | ALDH1A1 (0.43) | LMNAALDH1A1NPSR1USP2HTT | |
| SCHEMBL6960505 | 0.76 | LMNA (0.52) | PPARGLMNAALDH1A1NPSR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |