Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970661 | 0.89 | ALDH1A1 (0.46) | RAB9ASMN1; SMN2MAPTMEN1CYP1A2 | |
| SCHEMBL6969382 | 0.88 | LMNA (0.55) | RAB9AMAPTMEN1KMT2ALMNA | |
| SCHEMBL6964153 | 0.87 | SMN1; SMN2 (0.46) | CA1CA2CA9CA14RAB9A | |
| SCHEMBL6969797 | 0.87 | LMNA (0.44) | RAB9AMAPTMEN1CYP1A2KMT2A | |
| SCHEMBL6960127 | 0.86 | NPSR1 (0.49) | RAB9ASMN1; SMN2MAPTMEN1CYP1A2 | |
| SCHEMBL6969459 | 0.85 | ALDH1A1 (0.46) | RAB9ASMN1; SMN2MAPTMEN1CYP1A2 | |
| SCHEMBL6967645 | 0.85 | LOXL2 (0.40) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| SCHEMBL6972651 | 0.81 | ALDH1A1 (0.41) | RAB9AMEN1THRBCYP2C19KMT2A | |
| SCHEMBL6959155 | 0.79 | LMNA (0.50) | MAPTTHRBCYP2C19LMNAALDH1A1 | |
| SCHEMBL6968111 | 0.79 | ALDH1A1 (0.43) | RAB9ASMN1; SMN2MAPTMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |