Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969225 | 0.87 | MAPT (0.33) | NPSR1TERTMAPTHTTSMN1; SMN2 | |
| SCHEMBL6965624 | 0.85 | NPSR1 (0.36) | NPSR1MAPTHPGDHTTNOTUM | |
| SCHEMBL6974042 | 0.85 | TP53 (0.36) | NPSR1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL6961065 | 0.85 | KDM4E (0.39) | NPSR1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL6961068 | 0.85 | KDM4E (0.39) | NPSR1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL6964200 | 0.84 | MAPT (0.37) | NPSR1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL6973394 | 0.82 | MEN1 (0.42) | NPSR1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL6964074 | 0.81 | HSP90AA1 (0.42) | NPSR1MAPTHPGDHTTSMN1; SMN2 | |
| SCHEMBL7084513 | 0.81 | LMNA (0.39) | NPSR1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL6969927 | 0.80 | IDO1 (0.38) | NPSR1MEN1KMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |