Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.40 |
| ▸ | MMP9 | P14780 | 9/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 10/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MMP14 | P50281 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6787148 | 0.84 | MMP2 (0.51) | MMP2MMP9MMP3MMP1ADAM10 | |
| SCHEMBL6968740 | 0.83 | MMP2 (0.41) | MMP2MMP9MMP3MMP1ADAM10 | |
| SCHEMBL6977692 | 0.81 | MMP2 (0.40) | MMP2MMP9MMP3MMP1ADAM10 | |
| SCHEMBL6974852 | 0.74 | ADAMTS4 (0.43) | MMP2MMP9MMP3MMP1ADAM10 | |
| SCHEMBL28580846 | 0.67 | NPC1 (0.69) | SMN1; SMN2MAPTNPC1RAB9APOLB | |
| SCHEMBL6785924 | 0.67 | MMP2 (0.52) | MMP2MMP9MMP3MMP1ADAM10 | |
| SCHEMBL6782627 | 0.67 | MMP2 (0.56) | MMP2MMP9MMP3MMP1ADAM10 | |
| SCHEMBL6950104 | 0.66 | MMP13 (0.47) | MMP2MMP1ADAM10MMP13MMP14 | |
| SCHEMBL4816291 | 0.66 | ADAMTS4 (0.60) | MMP2MMP9MMP3MMP1ADAM10 | |
| SCHEMBL12152323 | 0.66 | MMP2 (0.61) | MMP2MMP9MMP3MMP1ADAM10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282614-B1 | HYDROXAMIC ACID DERIVATIVES | DARWIN DISCOVERY LTD (GB) | 2003-11-12 | — | — | EP | claimed |