Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 5/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | BCR | P11274 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 3/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783061 | 0.85 | MMP2 (0.45) | ADAMTS4MMP13ABL1BCRMMP1 | |
| SCHEMBL6786249 | 0.82 | ADAMTS4 (0.47) | ADAMTS4MMP13ABL1BCRMMP1 | |
| SCHEMBL6977692 | 0.79 | MMP2 (0.40) | ADAMTS4MMP13MMP1HDAC6HDAC1 | |
| SCHEMBL6788003 | 0.77 | MMP13 (0.43) | ADAMTS4MMP13MMP1HDAC6HDAC3 | |
| SCHEMBL6968740 | 0.75 | MMP2 (0.41) | ADAMTS4MMP13MMP1MMP2MMP14 | |
| SCHEMBL6785472 | 0.75 | MMP13 (0.44) | ADAMTS4MMP13CYP3A4LMNAPOLB | |
| SCHEMBL6967936 | 0.74 | MMP2 (0.40) | ADAMTS4MMP13MMP1HDAC2POLB | |
| SCHEMBL6788336 | 0.74 | MMP13 (0.44) | ADAMTS4MMP13CYP3A4LMNAPOLB | |
| SCHEMBL7119358 | 0.72 | MMP13 (0.44) | ADAMTS4MMP13CYP3A4LMNAPOLB | |
| SCHEMBL6969646 | 0.72 | HDAC6 (0.43) | HDAC6HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282614-B1 | HYDROXAMIC ACID DERIVATIVES | DARWIN DISCOVERY LTD (GB) | 2003-11-12 | — | — | EP | claimed |