Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | CYP21A2 | P08686 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6787212 | 0.85 | MMP2 (0.51) | MMP2MMP9ADAM10MMP1MMP3 | |
| SCHEMBL6786580 | 0.82 | ADAM10 (0.42) | MMP2MMP9ADAM10MMP1MMP3 | |
| SCHEMBL6968740 | 0.82 | MMP2 (0.41) | MMP2MMP9ADAM10MMP1MMP3 | |
| SCHEMBL6783113 | 0.82 | ADAMTS4 (0.43) | MMP2MMP9ADAM10MMP1MMP3 | |
| SCHEMBL6967936 | 0.81 | MMP2 (0.40) | MMP2MMP9ADAM10MMP1MMP3 | |
| SCHEMBL7090534 | 0.79 | ADAM10 (0.42) | MMP2MMP9ADAM10MMP1MMP3 | |
| SCHEMBL6974852 | 0.79 | ADAMTS4 (0.43) | MMP2MMP9ADAM10MMP1MMP3 | |
| SCHEMBL6782094 | 0.72 | CYP11B1 (0.44) | HDAC6DYRK1AHDAC1CYP17A1CYP21A2 | |
| SCHEMBL942582 | 0.69 | MMP13 (0.53) | MMP13 | |
| SCHEMBL6787117 | 0.68 | CYP11B1 (0.42) | ADAMTS4DYRK1AMMP13CYP17A1CYP21A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282614-B1 | HYDROXAMIC ACID DERIVATIVES | DARWIN DISCOVERY LTD (GB) | 2003-11-12 | — | — | EP | claimed |