Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 13/20 | 0.55 |
| ▸ | MMP3 | P08254 | 12/20 | 0.55 |
| ▸ | MMP2 | P08253 | 9/20 | 0.52 |
| ▸ | MMP8 | P22894 | 8/20 | 0.49 |
| ▸ | MMP9 | P14780 | 7/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967976 | 1.00 | MMP1 (0.55) | MMP1MMP3MMP2MMP8MMP9 | |
| SCHEMBL6961631 | 0.86 | CTSK (0.59) | MMP1MMP3MMP2 | |
| SCHEMBL6961636 | 0.86 | CTSK (0.59) | MMP1MMP3MMP2 | |
| SCHEMBL7357861 | 0.85 | MMP3 (0.62) | MMP1MMP3MMP2MMP8MMP9 | |
| SCHEMBL7357865 | 0.85 | MMP3 (0.62) | MMP1MMP3MMP2MMP8MMP9 | |
| SCHEMBL6964283 | 0.83 | MMP3 (0.65) | MMP1MMP3MMP2MMP8MMP9 | |
| SCHEMBL6964276 | 0.83 | MMP3 (0.65) | MMP1MMP3MMP2MMP8MMP9 | |
| SCHEMBL7426200 | 0.82 | MMP3 (0.59) | MMP1MMP3MMP2MMP8MMP9 | |
| SCHEMBL6968692 | 0.82 | MMP3 (0.56) | MMP1MMP3MMP2MMP8MMP9 | |
| SCHEMBL6968687 | 0.82 | MMP3 (0.56) | MMP1MMP3MMP2MMP8MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021424-B1 | THIADIAZOLE AMIDE MMP INHIBITORS | UPJOHN CO (US) | 2003-02-26 | — | — | EP | disclosed |