Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 9/20 | 0.59 |
| ▸ | MMP1 | P03956 | 8/20 | 0.56 |
| ▸ | MMP2 | P08253 | 4/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.54 |
| ▸ | MMP9 | P14780 | 3/20 | 0.53 |
| ▸ | MMP8 | P22894 | 3/20 | 0.53 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357865 | 0.97 | MMP3 (0.62) | MMP3MMP1MMP2CAPN1MMP9 | |
| SCHEMBL7357861 | 0.97 | MMP3 (0.62) | MMP3MMP1MMP2CAPN1MMP9 | |
| SCHEMBL7358578 | 0.93 | MMP3 (0.56) | MMP3MMP1MMP2CAPN1MMP9 | |
| SCHEMBL6961636 | 0.91 | CTSK (0.59) | MMP3MMP1MMP2CTSLCTSK | |
| SCHEMBL6961631 | 0.91 | CTSK (0.59) | MMP3MMP1MMP2CTSLCTSK | |
| SCHEMBL6964283 | 0.89 | MMP3 (0.65) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL6964276 | 0.89 | MMP3 (0.65) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL7357689 | 0.87 | MMP1 (0.68) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL7357677 | 0.87 | MMP1 (0.68) | MMP3MMP1MMP2MMP9MMP8 | |
| SCHEMBL7365921 | 0.86 | CTSK (0.59) | MMP3MMP1MMP2CTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |