Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.47 |
| ▸ | PTGFR | P43088 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972628 | 0.91 | RAB9A (0.58) | PYGLRAB9APPARGNR1H4TP53 | |
| SCHEMBL7332090 | 0.90 | PYGL (0.62) | PYGLRAB9APPARGNR1H4GRM4 | |
| SCHEMBL7372458 | 0.85 | RAB9A (0.57) | PYGLRAB9APPARGNR1H4GAA | |
| SCHEMBL6961250 | 0.85 | ALDH1A1 (0.54) | RAB9AGRM4TP53GAAALDH1A1 | |
| SCHEMBL8313578 | 0.85 | PYGL (0.56) | PYGLRAB9APPARGNR1H4GRM4 | |
| SCHEMBL27376893 | 0.82 | PYGL (0.54) | PYGLRAB9APPARGNR1H4ALDH1A1 | |
| SCHEMBL6968458 | 0.81 | HCAR3 (0.66) | RAB9AALDH1A1PTGFRNPC1MEN1 | |
| SCHEMBL8961733 | 0.81 | HCAR3 (0.66) | RAB9AALDH1A1PTGFRNPC1MEN1 | |
| SCHEMBL7331410 | 0.79 | GRM4 (0.59) | PYGLRAB9AGRM4TP53ALDH1A1 | |
| SCHEMBL8812458 | 0.78 | RAB9A (0.57) | PYGLRAB9APPARGTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |