Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CDC25B | P30305 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PTGFR | P43088 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968458 | 1.00 | HCAR3 (0.66) | HCAR3MEN1KMT2APOLBKCNMA1 | |
| SCHEMBL6963217 | 0.86 | KMT2A (0.64) | HCAR3MEN1KMT2APOLBKCNMA1 | |
| SCHEMBL6968515 | 0.81 | PYGL (0.57) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL2772166 | 0.80 | TSHR (0.65) | HCAR3MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL5696841 | 0.78 | TSHR (0.65) | HCAR3MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL14380933 | 0.76 | ALDH1A1 (0.53) | HCAR3MEN1KMT2AKCNMA1ALDH1A1 | |
| SCHEMBL3613079 | 0.75 | HCAR3 (0.72) | HCAR3MEN1KMT2ATSHRMAPT | |
| SCHEMBL2466950 | 0.74 | ABCB1 (0.52) | HCAR3MEN1KMT2APOLBKCNMA1 | |
| SCHEMBL19291300 | 0.74 | HCAR3 (0.70) | HCAR3MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6555690 | 0.73 | POLB (0.59) | HCAR3POLBALDH1A1CDC25BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |