Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780506 | 0.87 | MIF (0.39) | DGKALMNANAAAALDH1A1MAOA | |
| SCHEMBL11168898 | 0.86 | DGKA (0.51) | DGKALMNANAAAEPHX2ALDH1A1 | |
| SCHEMBL10700507 | 0.86 | DGKA (0.39) | DGKAEPHX2ALDH1A1DNM1 | |
| SCHEMBL9527125 | 0.81 | NAAA (0.39) | NAAA | |
| SCHEMBL8026346 | 0.76 | CHRM1 (0.37) | MAOAMAOB | |
| SCHEMBL1938997 | 0.75 | ALDH1A1 (0.38) | LMNANAAAALDH1A1 | |
| SCHEMBL789435 | 0.75 | NOS1 (0.35) | MAOAMAOB | |
| SCHEMBL8162908 | 0.74 | GNAO1 (0.48) | DGKAHTR2CNAAAEPHX2ALDH1A1 | |
| SCHEMBL254648 | 0.73 | GBA1 (0.33) | ALDH1A1MAOAMAOB | |
| SCHEMBL946963 | 0.72 | KMT2A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060178-B1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER (US) | 2003-09-03 | — | — | EP | claimed |
| US-6610707-B1 | Moderate neuronal regeneration and outgrowth and can be used for treating neurological disorders arising from neurodegenerative diseases and nerve damage. | PFIZER INC. | 2003-08-26 | — | — | US | claimed |