Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 11/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.34 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969252 | 1.00 | GRIN1 (0.38) | GRIN1GRIN2BS1PR3NOX4KMT2A | |
| SCHEMBL7084152 | 0.93 | S1PR3 (0.34) | GRIN1GRIN2BS1PR3NOX4ALDH1A1 | |
| SCHEMBL7084149 | 0.93 | S1PR3 (0.34) | GRIN1GRIN2BS1PR3NOX4ALDH1A1 | |
| SCHEMBL7085317 | 0.90 | ALDH1A1 (0.34) | S1PR3ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7085318 | 0.90 | ALDH1A1 (0.34) | S1PR3ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6971738 | 0.89 | GRM5 (0.35) | GRIN1GRIN2BS1PR3KMT2AALDH1A1 | |
| SCHEMBL6971733 | 0.89 | GRM5 (0.35) | GRIN1GRIN2BS1PR3KMT2AALDH1A1 | |
| SCHEMBL6967288 | 0.88 | GRIN1 (0.40) | GRIN1GRIN2BS1PR3NOX4KMT2A | |
| SCHEMBL6964467 | 0.85 | CFTR (0.42) | S1PR3KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL6964470 | 0.85 | CFTR (0.42) | S1PR3KMT2AALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |