Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971738 | 1.00 | GRM5 (0.35) | GRM5GRIN1GRIN2BALDH1A1KMT2A | |
| SCHEMBL6969157 | 0.93 | ADRA1D (0.32) | ALDH1A1KMT2AKDM4EMAPTTP53 | |
| SCHEMBL6969160 | 0.93 | ADRA1D (0.32) | ALDH1A1KMT2AKDM4EMAPTTP53 | |
| SCHEMBL7085318 | 0.90 | ALDH1A1 (0.34) | ALDH1A1KDM4ETP53LMNAHTT | |
| SCHEMBL7085317 | 0.90 | ALDH1A1 (0.34) | ALDH1A1KDM4ETP53LMNAHTT | |
| SCHEMBL6969251 | 0.89 | GRIN1 (0.38) | GRIN1GRIN2BALDH1A1KMT2AMAPT | |
| SCHEMBL6969252 | 0.89 | GRIN1 (0.38) | GRIN1GRIN2BALDH1A1KMT2AMAPT | |
| SCHEMBL6973903 | 0.88 | GRIN1 (0.38) | GRM5GRIN1GRIN2BALDH1A1KMT2A | |
| SCHEMBL6960641 | 0.86 | IDO1 (0.36) | ALDH1A1KMT2AKDM4EL3MBTL1MAPT | |
| SCHEMBL6960647 | 0.86 | IDO1 (0.36) | ALDH1A1KMT2AKDM4EL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |