Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086454 | 0.92 | ALOX12 (0.35) | ALOX12SLC6A9TP53RXFP1AKR1B1 | |
| SCHEMBL6975636 | 0.91 | ALOX12 (0.36) | ALOX12SLC6A9TP53RXFP1AKR1B1 | |
| SCHEMBL7081639 | 0.90 | ALOX12 (0.38) | ALOX12SLC6A9TP53RXFP1AKR1B1 | |
| SCHEMBL6968155 | 0.90 | TLR8 (0.34) | TLR8KDM4E | |
| SCHEMBL6974529 | 0.89 | DHODH (0.34) | SLC6A9MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL6960486 | 0.88 | IDO1 (0.34) | ALOX12SLC6A9TP53RXFP1AKR1B1 | |
| SCHEMBL8116257 | 0.88 | MEN1 (0.39) | TP53MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL6974700 | 0.86 | ALOX12 (0.35) | ALOX12SLC6A9TP53RXFP1AKR1B1 | |
| SCHEMBL6964051 | 0.85 | IRAK4 (0.35) | MEN1MAPTKMT2A | |
| SCHEMBL7086211 | 0.85 | ALDH1A1 (0.39) | TP53MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |