Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973001 | 0.92 | P2RX3 (0.33) | IDO1P2RX3SLC6A9CSNK2A2CSNK2B | |
| SCHEMBL6961900 | 0.92 | PIM1 (0.35) | IDO1P2RX3SLC6A9CSNK2A2CSNK2B | |
| SCHEMBL7082775 | 0.92 | TLR8 (0.33) | P2RX3TDP1MAPTKMT2A | |
| SCHEMBL7086211 | 0.92 | ALDH1A1 (0.39) | TP53LMNAKMT2A | |
| SCHEMBL7081541 | 0.91 | IDO1 (0.35) | IDO1P2RX3SLC6A9CSNK2A2CSNK2B | |
| SCHEMBL6975545 | 0.90 | GRIN1 (0.34) | SLC6A9MAPTTP53LMNA | |
| SCHEMBL6969304 | 0.88 | ALOX12 (0.36) | SLC6A9ALOX12AKR1B1PTGDR2MAPT | |
| SCHEMBL7086066 | 0.88 | KMT2A (0.36) | MAPTRXFP1LMNAKMT2AL3MBTL1 | |
| SCHEMBL6965960 | 0.87 | LMNA (0.34) | IDO1P2RX3SLC6A9CSNK2A2CSNK2B | |
| SCHEMBL6967782 | 0.86 | LMNA (0.39) | IDO1P2RX3CSNK2A2CSNK2BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |