Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 7/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | GOT1 | P17174 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CCL2 | P13500 | 1/20 | 0.43 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.43 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31381632 | 1.00 | AADAT (0.64) | AADATOPRM1OPRK1OPRL1GOT1 | |
| SCHEMBL22631177 | 0.79 | AADAT (0.58) | AADATGOT1KYAT1KYAT3NOTUM | |
| SCHEMBL3786010 | 0.78 | AADAT (1.00) | AADATGOT1KYAT1KYAT3NOTUM | |
| SCHEMBL16612984 | 0.78 | AADAT (1.00) | AADATGOT1KYAT1KYAT3NOTUM | |
| SCHEMBL3779303 | 0.78 | AADAT (1.00) | AADATGOT1KYAT1KYAT3NOTUM | |
| SCHEMBL769455 | 0.78 | BRD4 (0.49) | AADATOPRM1OPRK1OPRL1BRD4 | |
| SCHEMBL26017423 | 0.78 | BRD4 (0.49) | AADATOPRM1OPRK1OPRL1BRD4 | |
| SCHEMBL29557464 | 0.78 | BRD4 (0.49) | AADATOPRM1OPRK1OPRL1BRD4 | |
| Hydrochloric Acid SCHEMBL16612968 | 0.77 | AADAT (0.97) | AADATGOT1KYAT1KYAT3NOTUM | |
| Hydrochloric Acid SCHEMBL16612967 | 0.77 | AADAT (0.97) | AADATGOT1KYAT1KYAT3NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076501-B2 | Photogenerated reagents | LC SCIENCES LC | 2011-12-13 | — | — | US | disclosed |
| US-20100137600-A1 | Photogenerated reagents | LC SCIENCES LC | 2010-06-03 | — | — | US | disclosed |
| US-7544829-B2 | Photogenerated reagents | LC SCIENCES LC | 2009-06-09 | — | — | US | disclosed |
| US-20080009630-A1 | Photogenerated reagents | LC SCIENCES LC | 2008-01-10 | — | — | US | disclosed |
| US-7235670-B2 | Photogenerated reagents | Gao, Xiaolian | 2007-06-26 | — | — | US | disclosed |
| EP-1341759-A2 | 3-SUBSTITUTED OXINDOLE BETA 3 AGONISTS | ELI LILLY AND COMPANY (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002038544-A2 | 3-SUBSTITUTED OXINDOLE BETA 3 AGONISTS | ELI LILLY AND COMPANY (US) | 2002-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009630-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | AADAT 1342/4885OPRM1 4446/4885OPRK1 4083/4885 |
| US-20100137600-A1 | Photogenerated reagents | PPOX, PGR, GRHPR | AADAT 1342/4885OPRM1 4446/4885OPRK1 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.