Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1362672 | 0.84 | ALDH1A1 (0.50) | SMN1; SMN2TSHRALDH1A1PTGS1TDP1 | |
| SCHEMBL32677395 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRALDH1A1PTGS1TDP1 | |
| SCHEMBL142738 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRALDH1A1PTGS1TDP1 | |
| SCHEMBL32677394 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRALDH1A1PTGS1TDP1 | |
| SCHEMBL4385033 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRALDH1A1PTGS1TDP1 | |
| SCHEMBL28857872 | 0.80 | TSHR (0.47) | SMN1; SMN2TSHRALDH1A1PTGS1TDP1 | |
| SCHEMBL362353 | 0.80 | PTGS2 (0.57) | SMN1; SMN2TSHRALDH1A1PTGS1TDP1 | |
| SCHEMBL5515138 | 0.78 | TSHR (0.46) | SMN1; SMN2TSHRALDH1A1PTGS1TDP1 | |
| SCHEMBL1231281 | 0.78 | PTGS2 (0.55) | SMN1; SMN2TSHRALDH1A1PTGS1TDP1 | |
| SCHEMBL13292717 | 0.78 | SMN1; SMN2 (0.63) | SMN1; SMN2TSHRALDH1A1PTGS1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |