Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.57 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | GGT1 | P19440 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1231281 | 0.98 | PTGS2 (0.55) | PTGS2ALDH1A1PTGS1TDP1TSHR | |
| SCHEMBL27521208 | 0.94 | PTGS2 (0.52) | PTGS2ALDH1A1PTGS1TDP1TSHR | |
| SCHEMBL27603303 | 0.86 | TSHR (0.46) | PTGS2ALDH1A1PTGS1TDP1TSHR | |
| SCHEMBL3188087 | 0.85 | KDM4E (0.50) | PTGS2ALDH1A1PTGS1TDP1TSHR | |
| SCHEMBL3787231 | 0.84 | PTGS2 (0.50) | PTGS2ALDH1A1PTGS1TDP1TSHR | |
| SCHEMBL338196 | 0.84 | PTGS2 (0.68) | PTGS2ALDH1A1PTGS1TDP1TSHR | |
| SCHEMBL29432883 | 0.84 | PTGS2 (0.68) | PTGS2ALDH1A1PTGS1TDP1TSHR | |
| SCHEMBL907658 | 0.83 | ACHE (0.61) | PTGS2ALDH1A1PTGS1TDP1TSHR | |
| SCHEMBL1362672 | 0.82 | ALDH1A1 (0.50) | PTGS2ALDH1A1PTGS1TDP1TSHR | |
| SCHEMBL9297160 | 0.82 | MAPK1 (0.61) | PTGS2ALDH1A1PTGS1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994042-A | 9- (1- (2- (2-Acetoxyl) phenyl) -tetrazole) -andrographolide derivative, and preparation method and application thereof | 江西省中医药研究院 | 2024-11-22 | — | — | CN | claimed |
| CN-113429308-A | Process for synthesizing diclofenac sodium | 安徽普利药业有限公司 | 2021-09-24 | — | — | CN | claimed |
| CN-112778203-A | Process for the preparation of 1H-indazole-3-carboxylic acid derivatives and granisetron and lonidamine | 兰州交通大学 | 2021-05-11 | — | — | CN | claimed |
| CN-107973742-A | The method for preparing 3- indole ketone compounds | 重庆文理学院 | 2018-05-01 | — | — | CN | claimed |
| CN-101808514-A | bioactive aniline copolymers | AUCKLAND UNISERVICES LTD | 2010-08-18 | — | — | CN | claimed |
| CN-101654396-A | Conversion of a multihydroxylated-aliphatic hydrocarbon or ester thereof to a chlorohydrin | DOW GLOBAL TECHNOLOGIES INC US | 2010-02-24 | — | — | CN | claimed |
| CN-1976886-A | Conversion of multihydroxylated-aliphatic hydrocarbon or ester thereof to chlorohydrin | DOW GLOBAL TECHNOLOGIES INC (US) | 2007-06-06 | — | — | CN | claimed |
| CN-1681470-A | Agent for dyeing keratinous fibres | HENKEL KGAA (DE) | 2005-10-12 | — | — | CN | claimed |
| US-6737427-B2 | ADMINISTERING TO THE PATIENT SUFFERING WITH THE DISEASE CAUSED BY OVERPRODUCTION OF MUCIN SUCH AS CHRONIC OBSTRUCTIVE PULMONARY DISEASES INCLUDING ASTHMA, EMPHYSEMA, AND CHRONIC BRONCHITIS A MUCIN GLYCOPROTEIN SYNTHESIS INHIBITOR | GENAERA CORPORATION | 2004-05-18 | — | — | US | claimed |
| EP-0550866-B1 | Process for the preparation of vinyl-substituted aromatics from arylamines | HOECHST AG (DE) | 1996-10-09 | — | — | EP | claimed |
| US-5475176-A | Process for preparing vinyl-substituted aromatic compounds from arylamines | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-12-12 | — | — | US | claimed |
| EP-0550866-A2 | Process for the preparation of vinyl-substituted aromatics from arylamines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-14 | — | — | EP | claimed |
| US-4212989-A | ARYL ESTER SOLVENTS USED IN CATALYTIC CARBONYLATION FO ALCOHOLS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1980-07-15 | — | — | US | claimed |
| US-12397060-B2 | pHLIP®-mediated intracellular delivery of immuno-stimulatory compounds | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) | 2025-08-26 | — | — | US | disclosed |
| US-12290575-B2 | Fluorescent compound comprising a fluorophore conjugated to a pH-triggered polypeptide | UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES (US) | 2025-05-06 | — | — | US | disclosed |
| CN-118994042-A | 9- (1- (2- (2-Acetoxyl) phenyl) -tetrazole) -andrographolide derivative, and preparation method and application thereof | 江西省中医药研究院 | 2024-11-22 | — | — | CN | disclosed |
| EP-0065811-A1 | Disperse azopyrimidine dyestuffs | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-01 | — | — | EP | disclosed |
| US-4234733-A | PHENOL, ALIPHATIC ESTER OR ETHER, CARBON MONOXIDE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1980-11-18 | — | — | US | disclosed |
| US-4212989-A | ARYL ESTER SOLVENTS USED IN CATALYTIC CARBONYLATION FO ALCOHOLS | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1980-07-15 | — | — | US | disclosed |
| US-3956167-A | DISPLAY DEVICES | BECKMAN INSTRUMENTS, INC. (US) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12397060-B2 | pHLIP®-mediated intracellular delivery of immuno-stimulatory compounds | STING1, MAVS, IRF3 | PTGS2 1764/4885ALDH1A1 4863/4885PTGS1 1973/4885 |
| US-12290575-B2 | Fluorescent compound comprising a fluorophore conjugated to a pH-triggered polypeptide | NPPA, LNPEP, VIP | PTGS2 3538/4885ALDH1A1 2449/4885PTGS1 3237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.