SCHEMBL4385033

SCHEMBL4385033

Nc1ccccc1OC(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.49
TSHR P16473 3/20 0.49
ALDH1A1 P00352 6/20 0.48
PTGS1 P23219 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
ADRA2B P18089 1/20 0.48
LMNA P02545 1/20 0.43
RECQL P46063 1/20 0.43
MAPT P10636 4/20 0.42
KDM4E B2RXH2 4/20 0.42
GAA P10253 2/20 0.42
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
HSD17B10 Q99714 5/20 0.41
CFTR P13569 1/20 0.41
HPGD P15428 3/20 0.39
KMT2A Q03164 1/20 0.39
ESR1 P03372 1/20 0.39
ITGB3 P05106 1/20 0.39
ITGA2B P08514 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10765570 0.84 MMP2 (0.41) SMN1; SMN2TSHRALDH1A1PTGS1TDP1
SCHEMBL1362672 0.84 ALDH1A1 (0.50) SMN1; SMN2TSHRALDH1A1PTGS1TDP1
SCHEMBL143632 0.83 KDM4E (0.46) SMN1; SMN2TSHRALDH1A1PTGS1TDP1
SCHEMBL6971578 0.82 SMN1; SMN2 (0.49) SMN1; SMN2TSHRALDH1A1PTGS1TDP1
SCHEMBL32677395 0.82 SMN1; SMN2 (0.49) SMN1; SMN2TSHRALDH1A1PTGS1TDP1
SCHEMBL142738 0.82 SMN1; SMN2 (0.49) SMN1; SMN2TSHRALDH1A1PTGS1TDP1
SCHEMBL32677394 0.82 SMN1; SMN2 (0.49) SMN1; SMN2TSHRALDH1A1PTGS1TDP1
SCHEMBL1551324 0.81 CA12 (0.41) SMN1; SMN2TSHRALDH1A1PTGS1TDP1
SCHEMBL6170616 0.81 KMT2A (0.63) SMN1; SMN2TSHRALDH1A1TDP1LMNA
SCHEMBL1552057 0.81 MAPK1 (0.41) SMN1; SMN2TSHRALDH1A1PTGS1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1976937-B1 2-[[1-[[(2,3-DIHYDRO-2-OXO-1H-BENZIMIDAZOL-5-YL)AMINO]CARBONYL]-2-OXOPROPYL]AZO]-BENZOIC ACID AND A PROCESS FOR ITS PREPARATION BASF SE (DE) 2009-12-02 EP claimed
EP-0923537-B1 PROCESS FOR THE PREPARATION OF CONTRAST AGENTS NYCOMED IMAGING AS (NO) 2001-10-31 EP claimed
WO-2023228186-A1 CYCLIC PEPTIDES FOR TARGETING EPIDERMAL GROWTH FACTOR RECEPTOR AND MUTATIONS THEREOF FOR DRUG DELIVERY Ariel Scientific Innovations Ltd. (IL) 2023-11-30 WO disclosed
EP-0905170-B1 Polybenzoxazoles and polybenzothiazoles precursors QIMONDA AG (DE) 2013-10-30 EP disclosed
EP-1189974-B1 POLYBENZOXAZOLE PRECURSORS INFINEON TECHNOLOGIES AG (DE) 2003-05-21 EP disclosed
EP-1189974-A1 POLYBENZOXAZOLE PRECURSORS Infineon Technologies AG (DE) 2002-03-27 EP disclosed
EP-0905124-B1 o-amino(thio)phenol-carboxylic acids and their preparation INFINEON TECHNOLOGIES AG (DE) 2001-12-12 EP disclosed
EP-0905123-B1 o-amino(thio)phenol-carboxylic acids and their preparation INFINEON TECHNOLOGIES AG (DE) 2001-12-12 EP disclosed
WO-2001066619-A1 POLYBENZOXAZOLE PRECURSORS INFINEON TECHNOLOGIES AG (DE) 2001-09-13 WO disclosed
EP-0905124-A1 o-amino(thio)phenol-carboxylic acids and their preparation SIEMENS AKTIENGESELLSCHAFT (DE) 1999-03-31 EP disclosed
EP-0905123-A1 o-amino(thio)phenol-carboxylic acids and their preparation SIEMENS AKTIENGESELLSCHAFT (DE) 1999-03-31 EP disclosed
EP-0905170-A2 Polybenzoxazoles and polybenzothiazoles precursors SIEMENS AKTIENGESELLSCHAFT (DE) 1999-03-31 EP disclosed
EP-0271883-A2 Coloured water soluble compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1988-06-22 EP disclosed
EP-0100297-B1 BIS-1:2-CHROMIUM COMPLEXES OF DISAZO DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1986-01-08 EP disclosed
EP-0082117-B1 CHROMIUM COMPLEXES OF POLYAZO DYESTUFFS CIBA-GEIGY AG (CH) 1985-04-10 EP disclosed
EP-0100297-A1 Bis-1:2-chromium complexes of disazo dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1984-02-08 EP disclosed
EP-0014378-B1 TRIS- OR TETRAKISAZO-DYESTUFFS AND THEIR USE FOR DYEING LEATHER BASF Aktiengesellschaft (DE) 1981-11-04 EP disclosed
EP-0014378-A1 Tris- or tetrakisazo-dyestuffs and their use for dyeing leather BASF Aktiengesellschaft (DE) 1980-08-20 EP disclosed