Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971147 | 0.95 | PTGS2 (0.37) | SOAT2SOAT1PLA2G10TSHRCES2 | |
| SCHEMBL6962138 | 0.89 | KCNH2 (0.38) | ALDH1A1LMNACETP | |
| SCHEMBL6967901 | 0.82 | FFAR1 (0.37) | ALDH1A1LMNA | |
| SCHEMBL5002852 | 0.76 | LMNA (0.50) | SOAT2SOAT1TSHRCES2CES1 | |
| SCHEMBL21693932 | 0.75 | CES2 (0.49) | SOAT2SOAT1EPHX2FAAHTSHR | |
| SCHEMBL6962294 | 0.73 | FFAR1 (0.41) | TSHRTP53MAPK1ALDH1A1HTT | |
| SCHEMBL6965956 | 0.73 | EP300 (0.38) | SOAT1FAAHTSHRTP53CYP3A4 | |
| SCHEMBL8923210 | 0.73 | SOAT2 (0.59) | SOAT2SOAT1EPHX2FAAHTSHR | |
| SCHEMBL21693912 | 0.73 | MEN1 (0.49) | EPHX2FAAHTSHRMAPK1ALDH1A1 | |
| SCHEMBL28754558 | 0.73 | EP300 (0.49) | SOAT2SOAT1PLA2G10EPHX2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |