Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977865 | 0.91 | GPR119 (0.41) | GPR119KDM4EPKMLMNATHRB | |
| Hydrochloric Acid SCHEMBL7953851 | 0.91 | GPR119 (0.40) | GPR119KDM4EPKMLMNATHRB | |
| SCHEMBL6977329 | 0.82 | TGFBR1 (0.43) | GPR119KDM4EPKMBCHEACHE | |
| SCHEMBL6977326 | 0.82 | TGFBR1 (0.43) | GPR119KDM4EPKMBCHEACHE | |
| SCHEMBL6973933 | 0.82 | KDM4E (0.41) | GPR119KDM4EPKMBCHEACHE | |
| SCHEMBL6967652 | 0.81 | BCHE (0.51) | GPR119BCHEACHEMAPTNPSR1 | |
| SCHEMBL7752382 | 0.79 | GPR119 (0.42) | GPR119KDM4EPKMDPP4MAPT | |
| SCHEMBL6973594 | 0.78 | ITGB3 (0.44) | KDM4EBCHEACHELMNA | |
| SCHEMBL6973599 | 0.78 | ITGB3 (0.44) | KDM4EBCHEACHELMNA | |
| SCHEMBL23849943 | 0.77 | DPP4 (0.46) | GPR119KDM4EPKMLMNADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |
| EP-1098878-A1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | LABORATOIRE L. LAFON (FR) | 2001-05-16 | — | — | EP | disclosed |
| WO-2000003986-A1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | LABORATOIRE L. LAFON (FR) | 2000-01-27 | — | — | WO | disclosed |