Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 4/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964406 | 0.86 | KDM4E (0.41) | KDM4EPKMLMNATHRBMEN1 | |
| SCHEMBL6977865 | 0.85 | GPR119 (0.41) | KDM4EPKMLMNATHRBMEN1 | |
| Hydrochloric Acid SCHEMBL7953851 | 0.84 | GPR119 (0.40) | KDM4EPKMLMNATHRBMEN1 | |
| SCHEMBL6972128 | 0.82 | GPR119 (0.40) | KDM4EPKMLMNATHRBGPR119 | |
| SCHEMBL6968609 | 0.80 | GPR119 (0.39) | KDM4EPKMLMNATHRBGPR119 | |
| SCHEMBL6969250 | 0.80 | NPC1 (0.43) | KDM4EPKMLMNATHRBALDH1A1 | |
| SCHEMBL6966451 | 0.79 | KDM4E (0.45) | KDM4EPKMLMNATHRBGPR119 | |
| SCHEMBL7943624 | 0.79 | KDM4E (0.52) | KDM4EPKMLMNAGPR119L3MBTL1 | |
| SCHEMBL6964219 | 0.79 | ITGB3 (0.43) | KDM4EPKMLMNATHRBGPR119 | |
| SCHEMBL6971137 | 0.79 | KDM4E (0.41) | KDM4EPKMLMNATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |