Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081323 | 0.88 | ALDH1A1 (0.37) | RAB9ANPC1HPGDCA2CA1 | |
| SCHEMBL6962458 | 0.85 | RAB9A (0.41) | SMN1; SMN2RAB9ANPC1HPGDCA2 | |
| SCHEMBL8617900 | 0.79 | RAB9A (0.43) | SMN1; SMN2RAB9ANPC1HPGDCA2 | |
| SCHEMBL6969101 | 0.79 | MPO (0.40) | SMN1; SMN2RAB9ANPC1HPGDMEN1 | |
| SCHEMBL6972170 | 0.77 | KMT2A (0.38) | RAB9ANPC1HPGDCA2CA1 | |
| SCHEMBL649075 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL9028080 | 0.75 | L3MBTL1 (0.39) | HPGDMEN1KMT2AALDH1A1ALOX12 | |
| SCHEMBL8622920 | 0.74 | NOS1 (0.40) | SMN1; SMN2RAB9ANPC1HPGDCA2 | |
| SCHEMBL6972511 | 0.73 | ALOX5 (0.45) | ALDH1A1L3MBTL1 | |
| SCHEMBL9078769 | 0.72 | CYP19A1 (0.36) | SMN1; SMN2RAB9ANPC1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |