Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967103 | 0.94 | CASP1 (0.51) | CASP1PIN1CTSLCTSBCTSS | |
| SCHEMBL7231335 | 0.85 | CASP1 (0.47) | CASP1CTSLCTSBCTSSITGB3 | |
| Benzofuran SCHEMBL6973046 | 0.85 | CASP1 (0.47) | CASP1CTSLCTSBCTSSTYR | |
| SCHEMBL7394440 | 0.82 | PIN1 (0.60) | PIN1CTSLCTSBCTSSTYR | |
| SCHEMBL6967105 | 0.78 | CASP1 (0.50) | CASP1CTSLCTSBCTSSTYR | |
| SCHEMBL6973369 | 0.77 | EPHX2 (0.40) | CASP1PIN1ITGB3ITGA2BITGAV | |
| SCHEMBL5396475 | 0.76 | TYR (0.53) | CTSLCTSBCTSSTYRITGB3 | |
| SCHEMBL5396482 | 0.76 | TYR (0.53) | CTSLCTSBCTSSTYRITGB3 | |
| SCHEMBL6964129 | 0.74 | ITGB3 (0.59) | ITGB3ITGA2BITGAV | |
| SCHEMBL5416162 | 0.74 | TYR (0.55) | CTSLCTSBCTSSTYRITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133491-B1 | NOVEL BENZOFURANE DERIVATIVES, PREPARATION METHOD, USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2003-02-19 | — | — | EP | disclosed |