Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.38 |
| ▸ | ITGAV | P06756 | 3/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7231808 | 0.91 | EPHX2 (0.36) | EPHX2LMNAITGB3ITGAVITGA2B | |
| SCHEMBL6967103 | 0.82 | CASP1 (0.51) | ITGB3ITGAVITGA2BALDH1A1PIN1 | |
| SCHEMBL6972652 | 0.82 | ITGB3 (0.61) | LMNAITGB3ITGAVITGA2B | |
| Benzofuran SCHEMBL6973042 | 0.77 | CASP1 (0.48) | ITGB3ITGAVITGA2BPIN1CASP1 | |
| SCHEMBL7224008 | 0.75 | ITGB3 (0.53) | ITGB3ITGAVITGA2B | |
| SCHEMBL6977330 | 0.73 | SLC7A5 (0.44) | LMNAITGB3ITGA2BFFAR1 | |
| SCHEMBL7231335 | 0.73 | CASP1 (0.47) | EPHX2LMNAITGB3ITGA2BALDH1A1 | |
| SCHEMBL6973854 | 0.72 | CA12 (0.37) | LMNAALDH1A1PIN1KMT2AMEN1 | |
| SCHEMBL6978544 | 0.71 | ALDH1A1 (0.52) | ITGB3ITGA2BALDH1A1KMT2AMEN1 | |
| SCHEMBL4834857 | 0.68 | ITGB3 (0.46) | LMNAITGB3ITGAVITGA2BITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133491-B1 | NOVEL BENZOFURANE DERIVATIVES, PREPARATION METHOD, USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2003-02-19 | — | — | EP | disclosed |