Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967105 | 0.94 | CASP1 (0.50) | CASP1CTSLCTSBCTSSTYR | |
| SCHEMBL7231340 | 0.85 | CASP1 (0.47) | CASP1CTSLCTSBCTSSTYR | |
| Benzofuran SCHEMBL6973042 | 0.85 | CASP1 (0.48) | CASP1CTSLCTSBCTSSTYR | |
| SCHEMBL7394442 | 0.79 | TYR (0.52) | CASP1CTSLCTSBCTSSTYR | |
| SCHEMBL6967103 | 0.78 | CASP1 (0.51) | CASP1CTSLCTSBCTSSTYR | |
| SCHEMBL6964135 | 0.75 | ITGB3 (0.59) | ITGB3ITGA2BITGAV | |
| SCHEMBL6973856 | 0.71 | CA12 (0.37) | CTSBCTSSITGA4ITGB7ITGB3 | |
| SCHEMBL6978547 | 0.70 | ALDH1A1 (0.52) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL7231335 | 0.69 | CASP1 (0.47) | CASP1CTSLCTSBCTSSITGB3 | |
| SCHEMBL22764775 | 0.69 | CTSB (0.72) | CASP1CTSLCTSBCTSSITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133491-B1 | NOVEL BENZOFURANE DERIVATIVES, PREPARATION METHOD, USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2003-02-19 | — | — | EP | disclosed |