Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6975183 | 0.92 | ENPP2 (0.35) | ENPP2ALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL6967033 | 0.91 | ENPP2 (0.31) | ENPP2TBXA2RALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6974519 | 0.91 | ENPP2 (0.35) | ENPP2P2RX3 | |
| SCHEMBL6967408 | 0.90 | F10 (0.33) | ENPP2LMNAGRM2 | |
| SCHEMBL6972846 | 0.90 | P2RX3 (0.34) | TBXA2RALDH1A1SMN1; SMN2P2RX3CCR5 | |
| SCHEMBL6961399 | 0.89 | PPARG (0.35) | ENPP2LMNA | |
| SCHEMBL6970500 | 0.87 | P2RX3 (0.34) | ENPP2P2RX3 | |
| SCHEMBL6967126 | 0.86 | GRIN1 (0.37) | ENPP2GRM2S1PR3 | |
| SCHEMBL6973336 | 0.85 | ALDH1A1 (0.32) | ALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL7087537 | 0.85 | TBXA2R (0.31) | TBXA2RALDH1A1LMNASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |