Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7228562 | 0.86 | LMNA (0.37) | LMNATP53FFAR1PTPN1CA12 | |
| SCHEMBL7395989 | 0.81 | LMNA (0.44) | LMNATP53FFAR1PTPN1CA12 | |
| SCHEMBL6967103 | 0.78 | CASP1 (0.51) | FFAR1ITGB3ITGA2BALOX15 | |
| SCHEMBL7542381 | 0.77 | SLC7A5 (0.57) | SLC7A5LMNAPTPN1ITGB3ITGA2B | |
| SCHEMBL6977333 | 0.76 | SLC7A5 (0.44) | SLC7A5LMNATP53PTPN1KDM4E | |
| SCHEMBL6978544 | 0.75 | ALDH1A1 (0.52) | ITGB3ITGA2BKDM4ETDP1 | |
| SCHEMBL6973854 | 0.75 | CA12 (0.37) | LMNATP53FFAR1PTPN1CA12 | |
| Benzofuran SCHEMBL6973042 | 0.73 | CASP1 (0.48) | PSMB5ITGB3ITGA2B | |
| SCHEMBL6973369 | 0.73 | EPHX2 (0.40) | LMNAFFAR1ITGB3ITGA2B | |
| SCHEMBL7231335 | 0.73 | CASP1 (0.47) | LMNAITGB3ITGA2BKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133491-B1 | NOVEL BENZOFURANE DERIVATIVES, PREPARATION METHOD, USE AS MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2003-02-19 | — | — | EP | disclosed |