Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 14/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 14/20 | 0.46 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974366 | 0.92 | LTB4R (0.45) | LTB4RLTB4R2CXCR3AOC3ALDH1A1 | |
| SCHEMBL6961731 | 0.91 | ALDH1A1 (0.49) | LTB4RLTB4R2CXCR3AOC3ALDH1A1 | |
| SCHEMBL6971987 | 0.85 | ALDH1A1 (0.42) | AOC3ALDH1A1HTTRAB9AMCHR1 | |
| SCHEMBL6969688 | 0.82 | ALDH1A1 (0.46) | AOC3ALDH1A1HTTRAB9A | |
| SCHEMBL6972036 | 0.80 | ALDH1A1 (0.50) | CXCR3AOC3ALDH1A1HTTRAB9A | |
| SCHEMBL224352 | 0.79 | DAO (0.41) | AOC3ALDH1A1HTT | |
| SCHEMBL9078864 | 0.79 | ALDH1A1 (0.37) | AOC3ALDH1A1HTTRAB9A | |
| SCHEMBL6969265 | 0.77 | ALDH1A1 (0.41) | AOC3ALDH1A1HTTRAB9AMCHR1 | |
| SCHEMBL6971280 | 0.76 | L3MBTL1 (0.44) | ALDH1A1 | |
| SCHEMBL6970345 | 0.76 | ALDH1A1 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729459-B1 | PHENYL-ALKYL IMIDAZOLES AS H3-RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2003-03-12 | — | — | EP | disclosed |
| US-5578616-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, TREATMENT FOR GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | SCHERING CORPORATION (US) | 1996-11-26 | — | — | US | disclosed |