Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968841 | 0.89 | GAA (0.43) | L3MBTL1ICMTSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL30610416 | 0.78 | QPCT (0.53) | L3MBTL1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL22712390 | 0.78 | QPCT (0.53) | L3MBTL1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL5506124 | 0.77 | ALDH1A1 (0.64) | L3MBTL1ICMTALDH1A1MAPTGAA | |
| SCHEMBL9511988 | 0.77 | L3MBTL1 (0.46) | L3MBTL1SMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL2229559 | 0.76 | POLB (0.42) | SMN1; SMN2ALDH1A1MAPTGAAHTT | |
| SCHEMBL27489390 | 0.76 | SMN1; SMN2 (0.58) | L3MBTL1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL4158643 | 0.76 | SMN1; SMN2 (0.44) | L3MBTL1SMN1; SMN2ALDH1A1MAPTLMNA | |
| SCHEMBL11248471 | 0.74 | GAA (0.46) | ALDH1A1MAPTGAAHTTKMT2A | |
| SCHEMBL29563275 | 0.74 | SMN1; SMN2 (0.53) | L3MBTL1SMN1; SMN2MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021411-B1 | BENZAMIDE DERIVATIVES AS THROMBIN INHIBITORS | GLAXO GROUP LTD (GB) | 2003-03-05 | — | — | EP | disclosed |
| US-6326386-B1 | ANTICOAGULANT | GLAXO GROUP LIMITED (GB) | 2001-12-04 | — | — | US | disclosed |