Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963345 | 0.84 | NR1H2 (0.35) | SMN1; SMN2LMNACYP3A4CYP1A2CYP2C19 | |
| SCHEMBL6971952 | 0.78 | PIK3CD (0.34) | HTTMAPTL3MBTL1 | |
| SCHEMBL8345336 | 0.71 | NR1H2 (0.38) | SMN1; SMN2KMT2ALMNARAB9AMAPT | |
| SCHEMBL6975297 | 0.71 | NR1H3 (0.61) | SMN1; SMN2HTTKMT2ALMNACYP1A2 | |
| SCHEMBL2097653 | 0.65 | IDO1 (0.65) | SMN1; SMN2HTTKMT2ALMNACYP3A4 | |
| SCHEMBL8345513 | 0.64 | NPC1 (0.37) | SMN1; SMN2HTTKMT2ALMNARAB9A | |
| SCHEMBL27542850 | 0.64 | P2RX7 (0.60) | SMN1; SMN2HTTKMT2ALMNACYP3A4 | |
| SCHEMBL7740503 | 0.64 | NR1H2 (0.49) | SMN1; SMN2HTTKMT2ALMNARAB9A | |
| SCHEMBL9479565 | 0.63 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTKMT2ALMNACYP3A4 | |
| SCHEMBL13325845 | 0.62 | KMT2A (0.57) | SMN1; SMN2HTTKMT2ALMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123287-B1 | INSECTICIDAL 3- (SUBSTITUTED PYRIDYL) -1, 2, 4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2003-07-30 | — | — | EP | disclosed |
| US-6413992-B1 | 3-(substituted pyridyl)-1,2,4-triazole compounds | DOW AGROSCIENCES LLC | 2002-07-02 | — | — | US | disclosed |