Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971952 | 0.89 | PIK3CD (0.34) | HTR6PIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL8345336 | 0.87 | NR1H2 (0.38) | NR1H2NR1H3HTR6HDAC6ADCY10 | |
| SCHEMBL6975165 | 0.84 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2CYP1A2CYP3A4GAA | |
| SCHEMBL8345513 | 0.79 | NPC1 (0.37) | NR1H2NR1H3HDAC6LMNASMN1; SMN2 | |
| SCHEMBL6975297 | 0.75 | NR1H3 (0.61) | NR1H2NR1H3LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL11296201 | 0.66 | HTR6 (0.41) | HTR6ADCY10 | |
| SCHEMBL7740503 | 0.66 | NR1H2 (0.49) | NR1H2NR1H3LMNASMN1; SMN2GAA | |
| SCHEMBL8343347 | 0.66 | HCRTR1 (0.33) | LMNASMN1; SMN2PSEN1PSEN2APH1B | |
| SCHEMBL6972656 | 0.64 | MEN1 (0.47) | NR1H2NR1H3PIK3CDLMNASMN1; SMN2 | |
| SCHEMBL6967154 | 0.64 | NR1H2 (0.47) | NR1H2NR1H3SMN1; SMN2CYP2A6CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123287-B1 | INSECTICIDAL 3- (SUBSTITUTED PYRIDYL) -1, 2, 4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 2003-07-30 | — | — | EP | disclosed |
| US-6413992-B1 | 3-(substituted pyridyl)-1,2,4-triazole compounds | DOW AGROSCIENCES LLC | 2002-07-02 | — | — | US | disclosed |