Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985201 | 0.92 | EPHX2 (0.45) | POLBKMT2AMEN1LMNARAB9A | |
| Hydrochloric Acid SCHEMBL6978492 | 0.92 | EPHX2 (0.45) | POLBKMT2AMEN1LMNARAB9A | |
| SCHEMBL6984619 | 0.90 | LMNA (0.42) | TP53LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7983728 | 0.86 | CCR3 (0.33) | POLBCCR3 | |
| Hydrochloric Acid SCHEMBL6986361 | 0.85 | CCR3 (0.32) | POLBCCR3 | |
| SCHEMBL8311013 | 0.84 | EPHX2 (0.44) | POLBKMT2AMEN1MAPTLMNA | |
| SCHEMBL6980124 | 0.81 | CHRM1 (0.32) | — | |
| SCHEMBL6983686 | 0.81 | CHRM1 (0.32) | — | |
| Oxalic Acid SCHEMBL6980644 | 0.81 | GRM5 (0.42) | LMNARAB9ANPC1EPHX2 | |
| Mandelic Acid SCHEMBL9412809 | 0.81 | PRCP (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |