Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 5/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985201 | 0.92 | EPHX2 (0.45) | EPHX2DRD2DRD3ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL6978492 | 0.91 | EPHX2 (0.45) | EPHX2DRD2DRD3ALDH1A1POLB | |
| SCHEMBL6975786 | 0.84 | POLB (0.40) | EPHX2ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL8311005 | 0.83 | EPHX2 (0.45) | EPHX2DRD2DRD3ALDH1A1CCR5 | |
| Oxalic Acid SCHEMBL6983672 | 0.79 | BCHE (0.43) | DRD2DRD3CYP2D6LMNAHTT | |
| SCHEMBL6984619 | 0.79 | LMNA (0.42) | DRD2ALDH1A1CCR5LMNASMN1; SMN2 | |
| SCHEMBL6979549 | 0.78 | CHRM2 (0.44) | DRD2DRD3CYP2D6LMNAHTT | |
| SCHEMBL6983077 | 0.77 | SOS1 (0.39) | CARM1PRMT6MEN1KMT2AMAPT | |
| Oxalic Acid SCHEMBL6984301 | 0.77 | SLC6A4 (0.53) | — | |
| Hydrochloric Acid SCHEMBL6984600 | 0.77 | TPSAB1 (0.33) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | Takeda Chemical Industries, Ltd. (JP) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008842-A1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-05 | — | — | WO | disclosed |