Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CCR10 | P46092 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6969507 | 0.91 | ITGB3 (0.41) | ITGB3ITGA2BF2 | |
| SCHEMBL6974976 | 0.91 | CCR8 (0.40) | GPR119KDM4EPKMTGFBR1MMP13 | |
| SCHEMBL6963513 | 0.91 | GPR119 (0.41) | GPR119KDM4EPKMTGFBR1MMP13 | |
| SCHEMBL7951214 | 0.90 | TGFBR1 (0.44) | GPR119KDM4EPKMTGFBR1MMP13 | |
| SCHEMBL6964615 | 0.90 | CCR8 (0.42) | GPR119KDM4EPKMTGFBR1MMP13 | |
| SCHEMBL6967108 | 0.90 | GAA (0.45) | GPR119KDM4EPKMP2RX7F2 | |
| SCHEMBL6976329 | 0.89 | F2 (0.44) | ITGB3ITGA2BGPR119KDM4EF2 | |
| SCHEMBL6962633 | 0.89 | MMP13 (0.49) | ITGB3ITGA2BGPR119KDM4EPKM | |
| SCHEMBL6976930 | 0.88 | TGFBR1 (0.45) | F2TGFBR1F10PLGPLAU | |
| SCHEMBL6959037 | 0.88 | F2 (0.38) | GPR119KDM4EPKMF2TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098878-B1 | BISPIPERIDINES AS ANTITHROMBOTIC AGENTS | CEPHALON FRANCE (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-6333338-B1 | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | LABORATOIRE L. LAFON (FR) | 2001-12-25 | — | — | US | disclosed |